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A B12 deficiency in females can cause symptoms such as fatigue, tingling feet, or depression

Weight loss of 710% body weight can significantly reduce liver fat and inflammation in NAFLD

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Managing Side Effects The combination is generally well tolerated, but most patients experience at least mild side effects in the first 8 weeks

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This makes it particularly relevant in clinical contexts where someone has gut lining compromise alongside systemic inflammation, for example, long-term NSAID use for chronic pain