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Understanding how pregnancy protects against ovarian and endometrial cancer development: Fetal antigens may be involved
Figure 8 The picture emerging is that, in intact hearts, neuro-cardiac communication involves extra-cellular (first-messenger) signaling microdomains and intracellular (second messenger) micro/nanodomains which combine to control, with exquisite precision and flexibility, CM responses to SN activation

Xing Zhang View on Scopus Communications Medicine, Donglu Zhang

That is, low GSH could be due to low production of GSH OR it could be due to high production but also high reducing activity due to a high oxidative load (reflected in high levels of GSSG)

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VEGFR2 activation triggers downstream Akt phosphorylation and endothelial nitric oxide synthase signaling, raising nitric oxide output and supporting new vessel formation
