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Research has suggested BPC-157 may counteract effects of both L-NAME (NO synthase inhibition) and L-arginine (NO substrate overload) behaving as a *balancer* of NO signalling rather than a one-directional agonist or antagonist

[DOI] [PMC free article] [PubMed] [Google Scholar] [103].Henske EP, Jwiak S, Kingswood JC, Sampson JR, Thiele EA, Tuberous sclerosis complex, Nature Reviews Disease Primers, 2 (2016) 16035

Although there was no difference in absolute size compared to TD, ASD callosums were disproportionately small when adjusted for increased ASD cerebral volume

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