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These findings hinted that the decrease in the active tetrameric configuration of PKM2, brought on by the insulin-ATM signaling, is a downstream effector response regulating the catabolic versus anabolic fates of glucose and glutamine in cerebellum
Successful isolation and long-term establishment of a cell line with stem cell-like features from an anaplastic medulloblastoma
Gentamicin triggers RIPOR2 translocation from cochlear stereocilia to the pericuticular area in murine hair cells
Primary and secondary outcomes were measured at all timepoints (i.e., V1, V2, V3, V4, V5, and V6)
Collectively the prior work support moving forward with a Phase II, placebo-controlled study of D+Q (NCT04685590)
doi: 10.1007/s10637-011-9766-6 210 VoglDTMartinTGVijRHariPMikhaelJRSiegelDet al
