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Discussion Here we demonstrate here that selectively targeting the CD38 NADase ectoenzyme with the catalytically inhibitory heavy-chain monoclonal antibody can mitigate skin and lung fibrosis in mice

Progressive neurological deficits: If weakness is worsening despite treatment, medical evaluation is essential

Rajan S, Wallace JI, Brodkin KI, Beresford SA, Allen RH, Stabler SP

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The following protocols represent common clinical strategies, though individual optimization should involve healthcare provider guidance