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Moreover, polyunsaturated fatty acids (PUFAs) are prone to oxidation by ROS, Lipoxygenase enzymes, cytochrome P450 enzymes, and potentially other oxidative enzymes (Fig
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Neurology 99, 877878
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Due to its lipophilic nature, NFPS tends to accumulate within the plasma membrane, diffusing through the lipid bilayer until it reaches GlyT1
