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[DOI] [PMC free article] [PubMed] [Google Scholar] 29.Akyuz G, Kenis-Coskun O
Zelko, I
doi: 10.1155/2017/1835195
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Our body naturally tries to neutralize these toxic compounds through a powerful antioxidant called Glutathione
Thus, albeit initially the concerns on the use PDE5i for CAD treatment - due to the marginal beneficial effects - shifted their application from CVD to ED, thereafter, sildenafil was reallocated for the treatment of cardiac disorders, due to both endothelial and anti-inflammatory/pro-remodeling effects in cardiac cells (43)
