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elegans by treating them with a 1:2 mixture of 5N NaOH and 5% sodium hypochlorite solution for 10 min and then washing them 3

Additionally, fermented ginseng inhibited de novo lipogenesis via activation of the AMPK pathway and blocked P38 phosphorylation through the mitogen-activated protein kinase (MAPK) pathway, which resulted in a decrease in hepatic inflammation (You et al., 2020)

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These metabolites have been detected in both polar and non-polar extracts and may exhibit anti-inflammatory and antimicrobial activities (Molina-Calle et al., 2017)

TAMs are well-known parts of breast cancer microenvironment and most TAMs within TME are closely related to the M2-like phenotype, which participate in almost all metastatic processes, including local invasion, blood vessel intravasation, extravasation at distant sites and metastatic cell growth (287, 288).The hypoxic areas in tumors are related to the accumulation of macrophages, which assist tumor progression by producing angiogenic factors, mitogenic factors and cytokines related to tumor metastasis (289291)