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Nat Rev Drug Discovery 20:309325 Narita Y, Arakawa Y, Yamasaki F, Nishikawa R, Aoki T, Kanamori M, Nagane M, Kumabe T, Hirose Y et al (2019) A randomized, double-blind, phase III trial of personalized peptide vaccination for recurrent glioblastoma

The mechanisms are likely associated with restoring the balance of gut dysbiosis, increasing the enrichment of SCFA-producing bacteria, and upregulating the production of gut microbiota-derived acetate, which protected mice against IAV infection by enhancing IFN-I expression

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