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Following from previous work that sought to identify sequence determinants of S fibrillation, a library-based -lactamase tripartite fusion construct in which S was inserted between Blac fragments and probed for aggregation, identified mutations within the P1/P2 regions that impacted on the ability of S to aggregate
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10.1016/j.yjmcc.2012.09.002 J

Ferat-Osorio et al., 2014)
