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Adequate methionine (which must otherwise be obtained in the diet) is needed to make S-adenosyl-methionine, which is in turn necessary for methylation of myelin sheath phospholipids

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Getting bright light (ideally from the sun) in the morning and keeping lights dim as you prepare for sleep can help

Note that the patent includes some technical advances to the macrocycles that are not yet ready for publication

[DOI] [PubMed] [Google Scholar] 23.Cornick S, Tawiah A, Chadee K