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[DOI] [PubMed] [Google Scholar] Partilla JS, Dempsey AG, Nagpal AS, Blough BE, Baumann MH, Rothman RB

Chronic endoplasmic reticulum stress activates unfolded protein response in arterial endothelium in regions of susceptibility to atherosclerosis

Suspected patients should rapidly be transferred to centers with a pediatric ICU, where first-line medications and consensus-based written protocols should be 24 h/7d easily accessible

Age The blood levels of cholesterol tend to increase as we age--a factor doctors consider when when deciding treatment options for patients with certain cholesterol levels

The global unfolding observed with HDX-MS was confirmed by differential scanning fluorimetry (DSF) showing that the catalytic /-hydrolase domain unfolds with a T m of 34.8 C, which is well below normal body temperature [17]

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