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There are several examples of cereblon-based PROTACs recently reported in the literature starting from the building block 4-fluorothalidomide (Table 2)

The genomic landscape of cutaneous SCC reveals drivers and a novel azathioprine associated mutational signature

163 Taken together, the available evidence suggests that methotrexate treatment in rheumatoid arthritis is associated with a reduced risk of type 1 and type 2 diabetes, although the mechanisms underpinning the effects on glucose metabolism require further studies (Figure 3)

Towards nanomaterials for cancer theranostics: a system of DNA-modified magnetic nanoparticles for detection and suppression of RNA marker in cancer cells

GannonJMForrestPERoy ChengappaKN

Ferroptosis is regulated by many aspects of iron metabolism, including iron absorption, transport, storage, and utilization (section 4.1) [17]