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The time you take metformin depends on which type you use, as the maximum dosage of metformin varies

Silver, D

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& Taeb, A

Finally, we discuss emerging strategies to interrogate and modulate this circuit using integrated omics, CRISPR-based screening, and pharmacological approaches, emphasizing the need for context-aware and temporally controlled metabolic interventions to enhance T cellbased immunotherapies in solid tumors

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