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Bulk RNA sequencing revealed that gene expression changes were most pronounced in the MBH, where RAMP1/3 KO mice treated with sCT showed extensive differential expression of over 1,700 genes, while WT mice exhibited comparatively minor transcriptional shifts

Potential mechanisms involved in the beneficial effect of normal sleep on the vaccination response include: (i) the sleep-induced reduction in circulating immune cells that most likely accumulate into lymphatic tissues, increasing the probability to encounter antigens and trigger the immune response

The single study showing decreased b12 levels involved a specific high-risk population

The absence of introns may expedite the quick expression of HSPs and clarify how they can be expressed despite stressors such as heat that may disrupt RNA splicing [165]
