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Despite research efforts to understand the mechanism by which the redox signal is transmitted from oxidant to specific proteins and in particular how Grx is activated to reverse or put forward glutathionylation, much remains to be elucidated

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m , Liver samples from mice treated with AAV8-GFP (n=9) or AAV8-AGXT (n=10) were sectioned and stained with H&E (scale bar = 200 m)