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According to the paper, which was published in Science Translational Medicine, one of the clear-skinned participants ending up developing acne one week after recieving the vitamin B12 injection

Facial Disability Index and House-Brackmann scoring

Although methylcobalamin and adenosylcobalamin are the two coenzyme forms required for the bodys chemical reactions, their supplementation isnt more efficient than cyanocobalamin or hydroxocobalamin because all B12 forms must first be stripped of their side groups before conversion to the coenzyme forms (Obeid, 2015)

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