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furan glutathione adducts New insight into the molecular mechanism of protein cross-linking induced by cis-2-butene-1,4-dial, the metabolite of furan: Formation of 2-substituted pyrrole cross-links involving the cysteine and lysine residues Stable Isotope Dilution Analysis (SIDA)

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furan glutathione adducts New insight into the molecular mechanism of protein cross-linking induced by cis-2-butene-1,4-dial, the metabolite of furan: Formation of 2-substituted pyrrole cross-links involving the cysteine and lysine residues Stable Isotope Dilution Analysis (SIDA)

Peptide research has expanded considerably in recent years, with scientists investigating numerous synthetic peptide sequences across a wide range of laboratory disciplines

furan glutathione adducts New insight into the molecular mechanism of protein cross-linking induced by cis-2-butene-1,4-dial, the metabolite of furan: Formation of 2-substituted pyrrole cross-links involving the cysteine and lysine residues Stable Isotope Dilution Analysis (SIDA)

PLoS ONE 9(8): e103490

furan glutathione adducts New insight into the molecular mechanism of protein cross-linking induced by cis-2-butene-1,4-dial, the metabolite of furan: Formation of 2-substituted pyrrole cross-links involving the cysteine and lysine residues Stable Isotope Dilution Analysis (SIDA)

Following nickel purification (Figure 4A, lanes 2 and 3), the enriched fraction showed a high degree of purity and appropriate size as a monomer in absence of glutathione (lane 2) or as a dimer in the presence of glutathione (lane 3)

furan glutathione adducts New insight into the molecular mechanism of protein cross-linking induced by cis-2-butene-1,4-dial, the metabolite of furan: Formation of 2-substituted pyrrole cross-links involving the cysteine and lysine residues Stable Isotope Dilution Analysis (SIDA)

Treatments (10 g RC/DMSO or PBS/DMSO) were administered twice daily for one month, with luminescence monitoring

furan glutathione adducts New insight into the molecular mechanism of protein cross-linking induced by cis-2-butene-1,4-dial, the metabolite of furan: Formation of 2-substituted pyrrole cross-links involving the cysteine and lysine residues Stable Isotope Dilution Analysis (SIDA)

Funding Statement This work was jointly supported by the High-level Talents Introduction Project of Anhui Science and Technology University (DKYJ202303, DKYJ202405), China Postdoctoral Science Foundation (2025M770265), National Natural Science Foundation of China (No.32302687) and the Jiangsu Agriculture Science and Technology Innovation Fund (CX (24) 3084)

furan glutathione adducts New insight into the molecular mechanism of protein cross-linking induced by cis-2-butene-1,4-dial, the metabolite of furan: Formation of 2-substituted pyrrole cross-links involving the cysteine and lysine residues Stable Isotope Dilution Analysis (SIDA)

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