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20 If a first-line agent is ineffective, intolerable, or contraindicated, the ACR guideline recommends switching to another first-line agent before trying alternative agents

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In the Japanese market, it can be very hard for novel products, new innovations to reach the local market because generally, the older generation prefer to use something that they are more familiar with, he said

RPLC-ion-trap-FTMS method for lipid profiling of plasma: method validation and application to p53 mutant mouse model

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J Cardiovasc Thorac Res