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Impaired FAD-dependent enzyme activity is also detrimental to bloodbrain barrier (BBB) integrity, leading to downregulation of tight-junction proteins such as claudin-5 and occluding, increased permeability, and enhanced peripheral immune infiltration
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Neurology 93 , e1474e1484 (2019)
Nutrients 12 (5), 1344
Robert, X
G., Stefanello, N., Rubin, M
