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It is primarily investigated in models of obesity, muscle wasting (sarcopenia), and metabolic bioenergetics
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The third family, IGF-1 LR3, skips the GH-signaling step entirely, binding directly to the IGF-1 receptor on muscle tissue and activating the PI3K/Akt and MAPK pathways tied to cell growth
GROWTH HORMONE GH is a single chain protein with 191 amino-acids and two disulfide bonds
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Hydroxocobalamin has relatively few major drug interactions
