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SuLShenLClayburghDRNalleSCSullivanEAMeddingsJBet alTargeted epithelial tight junction dysfunction causes immune activation and contributes to development of experimental colitis
The active translocation and secretion of HMGB1 are extensively regulated by post-translational modifications (PTMs), including acetylation, phosphorylation, ADP-ribosylation, methylation, glycosylation, and oxidation[22]

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Furthermore, lipoic acid, an antioxidant with anti-inflammatory properties, attenuated oxidative stress and neurotoxicity in SOD1 G93A and SOD1 G85R Drosophila and cell culture models (Moura et al., 2015

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