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The most direct connection was revealed in a recent study, which showed that in methionine excess, transcripts of PPP genes were strongly induced (Walvekar et al., 2018)

Chem Res Toxicol 25: 769793

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Laurenza I, Colognato R, Migliore L et al (2008) Modulation of palmitic acid-induced cell death by ergothioneine: evidence of an anti-inflammatory action