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Not because of acute toxicity, but because serotonergic signaling amplified beyond therapeutic window at doses previously considered safe independently

Thats the question I would ask if I was a patient. ___ AP video journalist Javier Arciga contributed to this story from San Diego

Gradually increasing within standard ranges may help

[8] Novo Nordisk announced late at the 2025 European Association for the Study of Diabetes (EASD) annual meeting that in the REDEFINE 1 study, [9] cagrilintide provided clinically significant weight loss, with a mean reduction in body weight of 11.8% compared to 2.3% with placebo after 68 weeks, considering adherence of all participants to treatment