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The copper ion serves as an essential cofactor for enzymes involved in collagen cross-linking and antioxidant activity

Ma T, Lu W, Wang Y, Qian P, Tian H, Gao X, et al

Importantly, menstrual cycle-related metabolic variability reflects not only estradiol and progesterone oscillations but also integrated adaptations across the hypothalamicpituitaryadrenal axis, autonomic nervous system, immune signaling, and gut microbiota

(B-D) Reproduced with permission Copyright 2024, ACS Sensors [199]
Additionally, varying levels of inflammation affecting the ocular surface may be present (225)
17 , e14462 (2024)
