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SZ demonstrated significantly elevated FW in whole-brain gray ( p = .001) but not white matter ( p = .060)

The robust neuroregenerative capabilities and functional recuperation exhibited by the CNS in lower-order vertebrates make them an attractive experimental model for investigating the role and behavior of abnormal tau following TBI and neurodegeneration

187 Dehydroepiandrosterone (DHEA) Dehydroepiandrosterone (DHEA) is a hormone produced mainly in the adrenal cortex, with smaller amounts produced in the testes, ovaries, and brain

After several cycles of refinement and model building, the inhibitor was placed into the cryo-EM map

For the identification of druggable targets, we considered three classes of enzymes: tier-1 targets, tier-2 targets, and other enzymes. Tier-1 targets correspond to enzymes whose knockout impedes viral replication while having a minimal impact on the simulated cellular viability