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Phytoestrogens Phytoestrogens are substances that naturally occur in plants

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Additionally, in pregnant mice model, peripheral reproductive clock genes are reported to affect uterine physiology via Akt/FoxO1 pathway (91), and prostaglandin G/H synthase 2 (PTGS2) upregulating (92)

According to studies published in the Journal of Cancer Science and Therapy, glutathione depletion causes increased oxidative stress, which can lead to cancer

It is also essential for folate and related one-carbon metabolism, where FAD is required as a cofactor for methylenetetrahydrofolate reductase (MTHFR), a key folate-metabolizing enzyme

Vegeto E, Villa A, Della Torre S, Crippa V, Rusmini P, Cristofani R, Galbiati M, Maggi A, Poletti A