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Adrenal gland disorders, particularly in the setting of chronic liver disease, impair cortisol metabolism and may worsen hepatic injury

Promotes healthy liver function for detoxification

Kila, K (2019)

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Cardoso Frontiers in Nutrition.2021;[Epub] CrossRef Hepatokines and Non-Alcoholic Fatty Liver Disease: Linking Liver Pathophysiology to Metabolism Tae Hyun Kim, Dong-Gyun Hong, Yoon Mee Yang Biomedicines.2021

This activation is accompanied by a loss of cellular retinoids, and the synthesis of -smooth muscle actin (-SMA), and large quantities of the major components of the extracellular matrix including collagen types I, III, and IV, fibronectin, laminin and proteoglycans