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(2001) High-level chloroquine resistance in Sudanese isolates of Plasmodium falciparum is associated with mutations in the chloroquine resistance transporter gene Pfcrt and the multidrug resistance Gene Pfmdr1

NICE recommends more frequent injections (alternate days until no further improvement) for patients with neurological involvement

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When the body lacks adequate B12, it struggles to produce sufficient red blood cells, leading to decreased oxygen delivery to tissues and organs, resulting in fatigue, weakness, and lethargy

Other common reasons are a local injection-site reaction, your body adjusting to corrected levels, and an underlying deficiency that was more severe than expected

Injecting slowly over 5-10 seconds largely prevents this