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Collectively, these findings indicate that, under defined pathological and catalytic conditions, GSH can be repurposed from an antioxidant safeguard into a redox driver that amplifies oxidative stress and promotes cell death in tumor and inflammatory contexts

10.1016/0378-7753(76)80019-5 82 PallarolaD.Von BilderingC.PietrasantaL

Hepatology 41 , 13131321 (2005)
Sci Rep 2019
Similar content being viewed by others Introduction Alzheimer's disease, Parkinson's disease, Huntington's disease, and amyotrophic lateral sclerosis are typical neurodegenerative diseases (NDs) (Maragakis and Rothstein 2006) that can be identified by the gradually implemented death of specifically vulnerable neurons (Abdalkader et al
GR = Glutathione reductase
