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Berberine also has anti-inflammatory immunomodulatory effects: studies have shown that berberine antagonizes pro-inflammatory signaling pathways and inhibits immune cells from overproducing cytokines such as TNF-, IL-6, and IL-1 (94)
2017;102:e415e418
Subsequently, they conducted in vivo experiments to validate the tumor-suppressive role of MIEAP and found that the concurrent knockout of MIEAP and autophagy-related gene 5 (ATG5) accelerated TC development and induced the oncocytic phenotype in BRAF V600E -positive thyroid cells [169]
doi: 10.3233/JAD-150514 309 ChenLLFanYGZhaoLXZhangQWangZY
Retrieved November 4, 2021
JMIR AI 2 , e49023 (2023)
