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"Worse, current pharmacological treatments are effective for only about 50 percent of the people for whom they're prescribed

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The discovery in C

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Using a Xenopus egg-extract model, which uncouples DNA repair from gene transcription 26 , we determined that IDH1 inhibition increased DSB formation and decreased HR, which was rescued by KG (Fig

The GR isoform, which is widely expressed, results from the insertion of a single arginine residue (R452) between the two zinc fingers in the DNA-binding