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Most people feel a sense of energy and alertness after a coffee enema, and a small number of people experience adverse reactions

A detailed study of the N -glycosylation of GGT from the human liver and kidney showed tissue-specific and site-specific N -glycosylation of GGT in normal human tissues (West et al., 2010)

Additionally, NAC possesses mild but documented anticoagulant and platelet-inhibiting properties, meaning it can slightly thin the blood

Iron is known to catalyze the Fenton reaction, which can produce harmful free radicals, leading to oxidative stress

Ethics statement All experimental procedures were approved by the Ethical Committee of the Faculty of Veterinary Medicine of the University of Ghent, Belgium (approval number EC2011-113) and carried out in accordance with the approved guidelines and regulations

J Clin Exp Hepatol 12(5):13331348 Devarbhavi H et al (2023) Global burden of liver disease: 2023 update