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P -values for the group effect were extracted from the model coefficients, and significance was determined using false discovery rate correction (BenjaminiHochberg method), with adjusted P -value log 2 (1.25)

HDL Cell Signaling Many of HDLs cellular functions cell survival, proliferation, vasodilation -- are mediated by HDL-induced cell signaling cascades (780)

Nrf2 directly regulates the expression of SLC7A11, glutamate-cysteine ligase catalytic subunit (GCLC), glutamate-cysteine ligase modifier subunit (GCLM), and glutathione synthase (GSS), which catalyze GSH synthesis, thereby enhancing GPX4 activity and suppressing ferroptosis (Zhang, 2025)

doi: 10.1210/jc.2008-2054

(1987) Mammalian tyrosinasethe critical regulatory control point in melanocyte pigmentation

So far, there is limited information on the exact consequences of TBI-induced NF-B signaling in astrocytes on the resulting cell-autonomous and non-cell-autonomous reactions and their contribution to TBI outcome 54,55