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If youre tempted to give carnitine supplementation a try, the clear message from the recent science is as follows: c arnitine should not be taken on its own just before present exercise

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Renal OCTN2 expression and activity increase when the carnitine concentration is reduced in the plasma and/or glomerular filtrate, whereas OCTN2 mRNA expression levels remain unchanged in the gut, liver, or skeletal muscle [254], highlighting the central role of the kidney in maintaining carnitine homeostasis