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In contrast, the full (liposome-encapsulated) plasma level of ribavirin in EYPC-based liposomes (again after a single intravenous injection of 50 mg/kg in rats) was found to peak at only 1 millimolar and to rapidly decline (with a half-life of about 3 hours), with no observed difference between the 0 and 2% GSH on the outer surface of the liposomes
[DOI] [PMC free article] [PubMed] [Google Scholar] 40.Chen Y., Azad M.B., Gibson S.B
Top scorers were then analyzed for drug potentiation experimentally and their mechanisms of action were determined
Is there a more effective clinical treatment based on the different functions of autophagy
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