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Subsequently, O 2 will be rapidly converted into H 2 O 2 by manganese superoxide dismutase (MnSOD) within the mitochondrial matrix and then transmitted to the cytoplasm to participate in other biological reactions [40]
Curr Oncol Rep 13(3):206-15, 2011
When absorbed, citrulline is converted to arginine in the kidneys, which then serves as the primary substrate for nitric oxide production

(PubMed) Schoenen J, Jacquy J, Lenaerts M

The other historical doses (1 mg, 4 mg, 8 mg) remain Phase 2 / research reference points only
Nature 477 , 549555 (2011)
