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Leptin stimulated the production of superoxide anion (O2) via NADPH oxidase (through the PI3 K/Akt pathway), the expression of NOX2, and the levels of nitrotyrosine

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Multiple dosages of ALC administered intravenously and orally increased ALC CSF and plasma concentrations in Alzheimer's disease patients, suggesting that ALC efficiently passes the bloodbrain barrier (BBB) (Parnetti et al., 1992)

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A review of the toxicity of HIV medications