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Safety, tolerability and anti-tumour activity of the androgen biosynthesis inhibitor ASP9521 in patients with progressive metastatic castration-resistant prostate cancer (mCRPC): Multi-centre phase I/II study [abstract]

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Given the experimental and clinical advances with regard to the mechanisms of gut microbiota in the pathogenesis of CVD, there is great promise of finding new approaches to treat CVD by using gut microbial metabolites such as SCFAs and some types of BAs, or blocking the production of detrimental microbial metabolites such as TMAO with inhibitors