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We test every lot to confirm LPS-free material

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A study published in Endocrinology demonstrated that chronic treatment with the fragment in obese mice resulted in a reduction of adipose tissue mass without changes in lean body mass or food consumption

This NAD+ elevation activates sirtuins, particularly SIRT1 in adipocytes and hepatocytes, which deacetylates and activates numerous metabolic regulatory proteins including PGC-1, a master regulator of mitochondrial biogenesis, oxidative metabolism, and thermogenesis