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14 However, a subsequent 16-month Phase III trial found no significant benefit when 600 patients with early PD received 1.2 g/day, 2.4 g/day, or a placebo

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The systematic review of the literature we conducted to find evidence of the beneficial effects of substances advertised as brain doping on physical performance or the improvement of athletic performance did not yield satisfactory findings that could significantly resolve our doubts regarding the status of the considered compounds

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Oral formulations with absorption enhancement, specifically delayed-release capsules using arginine salt, have changed the calculus here