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[DOI] [PubMed] [Google Scholar] 31.Malaguarnera M., Gargante M.P., Cristaldi E., Colonna V., Messano M., Koverech A., Neri S., Vacante M., Cammalleri L., Motta M

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Current therapies primarily address symptoms and have notable limitations, underscoring the need for alternative approaches, including lifestyle-based interventions

The Journal of Clinical Investigation 114(1): 57-66

Protein detection was performed by chemiluminescence using the SuperSignal West Femto substrate (ThermoFisher) and visualised with an Odyssey Fc Imager (LI-COR)

Cultured cells have limited lifespans, restricting long-term investigations into processes like amyloid plaque accumulation, tau tangle formation, and progressive neuronal degeneration (Rodriguez-Jimenez et al., 2023)