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doi: 10.1038/s41577-022-00760-x 69 ZhouRTardivelBThorensBChoiITschoppJ

Proteomic analyses of Caenorhabditis elegans dauer larvae and long-lived daf-2 mutants implicates a shared detoxification system in longevity assurance

doi: 10.2174/1567205012666151020114607

doi: 10.1016/j.molmed.2023.02.005

Abstract Glutathione (GSH) is a ubiquitous intracellular peptide with diverse functions that include detoxification, antioxidant defense, maintenance of thiol status, and modulation of cell proliferation

2) Systematically clarifying the exercise dose-response of exercise intervention at various stages of the disease, with particular emphasis on the dynamic regulatory mechanisms during the acute stage of mild damage and the long-term sequelae phase