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Under this condition, bacteria might have developed adaptive mechanisms for de novo biosynthesis and salvage of purines, and thus, a concomitant alteration in uric acid metabolism

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Glutathione (GSH) is a tripeptide that constitutes one of the main intracellular reducing compounds

Therefore, targeting DTP cells is anticipated to provide new treatment opportunities for cancer patients, although our current knowledge of these DTP cells in treatment resistance remains limited

We showed that cellular survival was independent of the p53 status of those cells