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Moreover, in breast cancer, IGF-1 mainly upregulates cysteine-rich 61 (Cyr61) by activating the PI3K/AKT pathway and an increase in Cyr61 promotes the growth and invasion of breast cancer cells (27)

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[DOI] [PMC free article] [PubMed] [Google Scholar] 178.Liu Y., Chen Z., Li B., Yao H., Zarka M., Welch J., Sachdev P., Bridge W., Braidy N

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