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These factors are tied to fertility

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"FOXO4-DRI improves spermatogenesis in aged mice through reducing senescence-associated secretory phenotype secretion from Leydig cells"
Moreover, EP supplementation ameliorated gut dysbiosis induced by high-fat diet, through the increase of short-chain fatty acid (SCFA)-producing bacteria and gut-barrier-protective microbe, and the reduction of endotoxin-producing bacteria [70]

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Materials and Methods Chemicals Aspirin (acetylsalicylic acid, ASA), cytochrome c, reduced and oxidized glutathione, (GSH and GSSG), 1-chloro 2,4-dinitrobenzene (CDNB), cumene hydroperoxide, glutathione reductase, 5,5-dithio bis-2-nitrobenzoic acid (DTNB), 2-thiobarbituric acid, buthionine sulfoximine (BSO), N-acetylcysteine (NAC), NADH, NADPH, coenzyme Q2, antimycin A, dodecyl maltoside and ATP bioluminescent somatic cell assay kit were purchased from Sigma-Aldrich Fine Chemicals (St Louis, MO, USA)
