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Animal model research reveals remarkable efficacy in both accelerated and natural aging conditions, with XpdTTD/TTD mice (accelerated aging model) showing restoration of multiple age-related deficits including fitness, fur density, and renal function following FOXO4-DRI administration

Logistic regression classification with Lasso regularization was performed using glmnet v4.1.1 with leave-one-out cross-validation to select the optimal regularization parameter

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[Google Scholar] Urist M

In some embodiments, the immunotherapy can be CAR (chimeric antigen receptor) -T therapy, wherein T cells are engineered to express a CAR comprising an antigen binding domain specific for an antigen on a tumor cell of interest

Pseudomonas putida attunes morphophysiological, biochemical and molecular responses in Cicer arietinum L