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Inflammatory cytokines activate immune cells, generating ROS and causing oxidative damage

While HMGB1 contributes to the development of hepatic steatosis, it may also lead to the activation of Kupffer cells and the exacerbation of inflammation [227]

Torres W, Prez JL, Daz MP, DMarco L, Checa-Ros A, Carrasquero R, et al

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A comprehensive understanding of glutamine metabolism can facilitate a more precise estimation of the potential anticancer targets and offer valuable clinical guidance

doi: 10.1155/2016/7909186
