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Step 3: protonation and product formation The now protonated Glu 103 acts as a general acid, donating a proton to C-1 of the enediol intermediate
doi: 10.1038/ng.257, PMID: [DOI] [PMC free article] [PubMed] [Google Scholar] 46.Kozlitina J, Smagris E, Stender S, Nordestgaard BG, Zhou HH, Tybjaerg-Hansen A, et al
A codified approach is needed to determine the potential indications of a search for high serum cobalamin and the practical clinical strategy to adopt upon discovery of elevated cobalamin levels
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