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Consequences of Low NAD+ Levels Fatigue and slow recovery: Mitochondrial inefficiency leads to ATP shortages

Two common reconstitution setups: 6mL BAC water 5mg/mL same concentration as the popular R-10 setup, 40 IU per 2mg dose 3mL BAC water 10mg/mL smaller injection volume, 20 IU per 2mg dose The R-30 works out to roughly $6/mg vs $7/mg for R-10 a meaningful difference when you're dosing weekly for months

doi: 10.1084/jem.190.7.915 12 AhmadRSorrellMFBatraSKDhawanPSinghAB

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Advanced / Loading Phase (Optional) Some protocols use a higher TB-500 loading dose during the first 24 weeks based on clinical monograph recommendations [5]